Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) are a popular chemogenetic technology for manipulation of neuronal activity in uninstrumented awake animals with potential for human applications as well. The
Hebbian plasticity, as represented by long-term potentiation (LTP) and long-term depression (LTD) of synapses, has been the most influential hypothesis to account for encoding of memories. The evidence for the
Our research is confined between the synaptic and circuit levels. We investigate the mechanisms behind associative and fear memories, the proteins necessary for memory formation, and the synaptic and molecular processes of memory decay.